Nutrition and Metabolism PhD Program
Nutrition researchers are a critical part of our society as they examine the complex interplay between nutrients, health, and disease, spanning from the individual to populations. With careers as faculty or independent scientists in academia, industry, and government, graduates of the Nutrition and Metabolism (N&M) PhD Program are at the forefront of research. They are making important contributions linking diet to the maintenance of health and impact on disease prevalence, and educating the public on the critical role of diet in the maintenance of optimal health throughout the life cycle.
Research
52 faculty trainers across 17 departments provide extensive interdisciplinary training opportunities in molecular, human and animal nutrition research.
Program Requirements
Our flexible curriculum provides core nutrition and metabolism coursework, with ample opportunities for elective coursework and minors.
Student Life
Gain a world-class education in a world-class city. Madison is a vibrant and inclusive community, and is consistently ranked as one of the best places to live in the U.S. for quality of life.
“Whether you’re driven by discovery, problem-solving, or the pursuit of knowledge, we look forward to helping you shape your research journey and make meaningful contributions to your field.“
-Dr. Rick Eisenstein, Director of Graduate Studies
News & Events
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MANTP alum Reji Babygirija awarded UW Distinguished Research Fellowship
T32 Metabolism and Nutrition Training Program (MANTP) alum Dr. Reji Babygirija was awarded a UW Distinguished Research Fellowship for her postdoctoral work related to the RISE-THRIVE initiative. The intent of the UW DRF Program is to support exceptional emerging scholars from around the world in collaborative research that takes place at UW–Madison and spans two…
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N&M students present at 2025 LABBSA Conference
N&M grad students Mark Heggen and Morgan Smith of the van Pijkeren lab presented their research at the 2025 Lactic Acid Bacteria Biology, Symbioses and Applications conference. Mark presented a poster entitled, “(p)ppGpp-mediated Resistance to an Antimicrobial Secondary Metabolite Promotes Gut Fitness.” Morgan gave a talk entitled, “Dietary Carbohydrates Alter Antimicrobial Sensitivity.”
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Crystal Qing receives John Brandt Memorial Scholarship for research on WPPC
Congrats to N&M PhD student Crystal Qing of the Leone lab, who was awarded the John Brandt Memorial Scholarship for her research investing the nutritional value and health benefits of Whey Protein Phospholipids Concentrate (WPPC)!
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Dr. Wei Wei joins N&M faculty trainer roster
The Nutrition and Metabolism Graduate Program (N&M) is happy to welcome Dr. Wei Wei as our newest faculty trainer. Dr. Wei will be starting as an Assistant Professor in the Department of Biochemistry in Fall 2025. Dr. Wei’s research studies the biochemical pathways that regulate nutrient metabolism in mammals. Welcome, Dr. Wei!
Recent Publications
Hermanson JB, Tolba SA, Gazi MA, Chrisler EA, Kaur M, Sidebottom AM, Liu Y, Martinez-Boggio G, Lucas LN, Amador-Noguez D, Rey FE, Leone VA. Gut microbes mediate the synergistic effects of dietary cholesterol and saturated fat in driving fibrosing MASH. Gut Microbes. 2026 Dec 31;18(1):2668121.
Wagner MR, Pintozzi NG, Schoff BM, Gold MI, Kasper RH, Steele NG, Blum B. Stromal and Neuronal Sources of Slit2/3 Ligands in the Adult Pancreas Exhibit Distinct Expression Patterns Independent of Robo2 Receptor Expression in the Islet. bioRxiv [Preprint]. 2026 May 18:2026.05.15.725534.
Knopf BA, Grunow I, Anderson B, Rihawi T, Sonsalla MM, Calubag MF, Babygirija R, Liu Y, Xiao F, Yeh CY, Lamming DW. Female resistance to the metabolic benefits of protein restriction is reversed by ovariectomy in mice. bioRxiv [Preprint]. 2026 Apr 3:2026.03.31.715667.
Williams J, Kim WS, Danner R, Cho J, Silva BF, Harris DA, Rey FE, Chaudhari SN. Atlas of one-carbon metabolism in conventional and germ-free mice reveals folate as a key determinant of biochemical pathways. Nat Metab. 2026 Apr;8(4):924-940.
Cho J, Danner R, Kim WS, Williams J, Singh A, Han JA, Van Vranken JG, Walker AS, Rhoads T, Chaudhari SN. Microbial metabolism of methotrexate produces a STAT3 signaling molecule that alleviates gut inflammation. bioRxiv [Preprint]. 2026 Mar 12:2026.03.11.711168.
McGregor ER, Osterbauer KJ, Gustafson GE, Clark JP, Rhoads TW, Anderson RM. Adiponectin and aging: Mechanistic insights, clinical paradox, and therapeutic horizons. Ageing Res Rev. 2026 May;117:103059.
Armstrong MT, Antunes K, Willis NB, Meyer MB, Pierre JF, Ozturk G. Whey Protein Phospholipid Concentrate and Its Fractions as a Diet Intervention Enhance Bone Health and Alter the Gut Microbiome in Weanling Mice. FASEB J. 2025 Dec 15;39(23):e71260. doi: 10.1096/fj.202502683R. PMID: 41363910; PMCID: PMC12687760.
Trautman ME, Green CL, MacArthur MR, Chaiyakul K, Alam YH, Yeh CY, Babygirija R, James I, Gilpin M, Zelenovskiy E, Green M, Marshall RN, Raskin A, Sonsalla MM, Flores V, Simcox JA, Ong IM, Malecki KC, Jang C, Lamming DW. Dietary isoleucine content modulates the metabolic and molecular response to a Western diet in mice. Mol Metab. 2025 Nov;101:102248.
Hermanson JB, Tolba SA, Gazi MA, Chrisler EA, Kaur M, Sidebottom AM, Liu Y, Martinez-Boggio G, Lucas LN, Amador-Noguez D, Rey FE, Leone VA. Gut microbes mediate the synergistic effects of dietary cholesterol and saturated fat in driving fibrosing MASH. bioRxiv [Preprint]. 2025 Jul 21:2025.07.16.665145.
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