Rozalyn Anderson

    Professor of Medicine

    Department of Medicine

    Nutrient sensitive regulatory pathways in aging and age-associated disease

    Office Location

    Veterans Administration Hosp
    2500 Overlook Ter GRECC D5214
    Madison WI 53705-2254

    Photo of Rozalyn Anderson

    Dr. Rozalyn Anderson is a faculty member of the Division of Geriatrics and Gerontology and the Division of Endocrinology, Diabetes and Metabolism in the Department of Medicine. She is affiliated with the Department of Nutritional Sciences and the Institute on Aging. She serves as Health Officer at the Geriatric Research Education and Clinical Center at the William S. Middleton Memorial Veterans Hospital. Her research focuses on the fundamental biology of aging and what creates the age-associated increase in vulnerability to a spectrum of diseases and disorders including cancer, diabetes, cardiovascular disease, and neurodegeneration.

    • The Sixth Annual Symposium of the Midwest Aging Consortium
      Ines Sturmlechner, Sarah A Ashiqueali, Hélène Martini, Karla Valdivieso, Ana Catarina Franco, Prashanth Guthikonda, Andrew J Dosch, Luis I Prieto, Niels C Asmussen, Amanda S Latham, James T Redden, Ethan A Leitschuh, Douglas G Mashek, João F Passos, Jhonny Rodriguez-Lopez, T Blake Monroe, David A Bernlohr, Paul D Robbins, Bailey A Knopf, Dudley W Lamming, Matthew J Johnston, Holly M Brown-Borg, Spencer A Tye, Timothy W Rhoads, David M Gate, Bennett G Childs, Darren J Baker, Xinna Li, In Hwa Jang, Christina D Camell, Zachary Miller, Hemali Phatnani, Adam R Konopka, Andrew J Haak, Natalia Vanegas-Avendano, Ramya N Akula, Ajinkya R Limkar, William A Ricke, Scott F Leiser, Jacinta Correia, Hua Bai, Szczepan Olszewski, Kenneth L Seldeen, G R Scott Budinger, Luisa C Morales-Nebreda, Deborah R Winter, Shelly K Mccrady-Spitzer, Rozalyn M Anderson, Maria M Mihaylova, Mauricio Rojas, Ana L Mora, Nathan K Lebrasseur, Marissa J Schafer
    • Aging-linked systemic lipid signature is reprogrammed by caloric restriction in rhesus monkeys
      Salma I Abou Elhassan, Josef P Clark, Di Kuang, Timothy W Rhoads, Ricki J Colman, Joshua J Coon, Rozalyn M Anderson, Katherine A Overmyer
    • Caloric Restriction Reprograms Adipose Tissues in Rhesus Monkeys
      Josef P Clark, Timothy W Rhoads, Sean J McIlwain, Michael A Polewski, Derek M Pavelec, Ricki J Colman, Rozalyn M Anderson
    • Author Correction: ImAge quantitates aging and rejuvenation
      Martin Alvarez-Kuglen, Kenta Ninomiya, Haodong Qin, Delany Rodriguez, Lorenzo Fiengo, Chen Farhy, Wei-Mien Hsu, Brian Kirk, Aaron Havas, Collin Kaufman, Gen-Sheng Feng, Amanda J Roberts, Rozalyn M Anderson, Manuel Serrano, Peter D Adams, Tatyana O Sharpee, Alexey V Terskikh
    • Position paper: leveraging non-human primate (NHP) specificities to accelerate Parkinson's disease and ageing research
      Erwan Bezard, Rozalyn M Anderson, Romina Aron Badin, Hagai Bergman, Ashley Boehringer, Simon Borgognon, Marina E Emborg, Jeffrey H Kordower, Jia-Yi Li, Anne-Caroline Martel, Jeanette M Metzger, Yoland Smith, Masahiko Takada, Jun Takahashi, Ryosuke Takahashi, Benjamin Dehay
    • Depth-dependent contributions of various vascular zones to cerebral autoregulation and functional hyperemia: An in-silico analysis
      Hadi Esfandi, Mahshad Javidan, Rozalyn M Anderson, Ramin Pashaie
    • The ongoing challenge of slowing ageing through drug discovery
      David G Le Couteur, Stephen J Simpson, Victoria C Cogger, Janani Thillainadesan, Rozalyn Anderson, Rafael de Cabo
    • Caloric restriction reprograms adipose tissues in rhesus monkeys
      Josef P Clark, Timothy W Rhoads, Sean J McIlwain, Michael A Polewski, Derek M Pavelec, Ricki J Colman, Rozalyn M Anderson
    • Neuron-specific isoform of PGC-1α regulates neuronal metabolism and brain aging
      Dylan C Souder, Eric R McGregor, Josef P Clark, Timothy W Rhoads, Tiaira J Porter, Kevin W Eliceiri, Darcie L Moore, Luigi Puglielli, Rozalyn M Anderson
    • Test of Rapamycin in Aging Dogs (TRIAD): study design and rationale for a prospective, parallel-group, double-masked, randomized, placebo-controlled, multicenter trial of rapamycin in healthy middle-aged dogs from the Dog Aging Project
      Amanda E Coleman, Kate E Creevy, Rozalyn Anderson, May J Reed, Virginia R Fajt, Kathleen M Aicher, Genna Atiee, Brian G Barnett, Ryan D Baumwart, Beth Boudreau, Suzanne M Cunningham, Matthew D Dunbar, Bobbie Ditzler, Anna M Ferguson, Kiersten K Forsyth, Anya N Gambino, Sonya G Gordon, Hillary K Hammond, Sydney N Holland, Mary K Iannaccone, Kate Illing, Saki Kadotani, Shelby A Knowles, Evan L MacLean, Brian A Maran, Lauren E Markovic, Stephanie McGrath, Rachel L Melvin, Mikaela S Mueller, O Lynne Nelson, Natasha J Olby, Theresa E Pancotto, Elizabeth Parsley, Brianna M Potter, Jena O Prescott, Ashley B Saunders, Holly M Sawyer, Brian A Scansen, Sarah M Schmid, Courtney C Smith, Sonja S Tjostheim, M Katherine Tolbert, Melissa A Tropf, Lance C Visser, Jessica L Ward, Sonya R Wesselowski, Rebecca C Windsor, Vicky K Yang, Audrey Ruple, Daniel E L Promislow, Matt Kaeberlein, Dog Aging Project Consortium
    • Symposia Report of The Annual Biological Sciences Section Meeting of the Gerontological Society of America 2023, Tampa, Florida
      Blanka Rogina, Rozalyn Anderson, Nathan K LeBrasseur, Sean P Curran, Matthew J Yousefzadeh, Bhaswati Ghosh, Gustavo Duque, Susan Howlett, Steven Austad, Ilja Demuth, Denis Gerstorf, Justin Korfhage, David B Lombard, Peter Abadir, Kaare Christensen, James R Carey, Susan C Alberts, Fernando Campos, Juan Pablo Palavicini, Allyson Palmer, Justice Bell, Nathan Basisty, Rafael de Cabo, Ana Gomes, Vishwa Deep Dixit, Payel Sen, Joseph A Baur, Shin-Ichiro Imai, Xiaoling Li, Gregorio Valdez, Miranda E Orr, Scott Pletcher, Julie Andersen, Leanne Jones, David Castillo-Azofeida, Michael Bonaguidi, Yousin Suh, Francesca E Duncan, Anna Murray, Meng C Wang, Kristopher Burkewitz, Mike Henne, Kai Zhou, Mustapha Bouhrara, Dan Benjamini, Shannon Kolind, Keenan A Walker, David A Reiter, Douglas C Dean, Vera Gorbunova, Vadim N Gladyshev, Robert Palovics, Laura J Niedernhofer, Rong Fan, Andreas D Bueckle, Jennifer Hurley, Karyn A Esser, Pankaj Kapahi, Shogo Sato, Nisi Jiang, Sarah A Ashiqueali, Jose Diaz, Sidharth Prasad Mishra, Nuno Raimundo, Reema Banarjee, Richard Allsopp, Lindsay M Reynolds, Bohan Zhang, Paola Sebastiani, Stefano Monti, Nicholas Schork, Noa Rappaport
    • Reversal of neuronal tau pathology via adiponectin receptor activation
      Eric R McGregor, Danny J Lasky, Olivia J Rippentrop, Josef P Clark, Samantha Wright, Mathew V Jones, Rozalyn M Anderson
    • The Fifth Annual Symposium of the Midwest Aging Consortium
      Brenda F Reader, Lorena Rosas, Bailey Anna Knopf, Yang Liu, Diego Alzate-Correa, Ajay Bhat, Anna Carey, Ana Maria Cuervo, Sanjana Dayal, Rafael S Demarco, Christian J Elliehausen, Davis A Englund, Haylee L Hamilton, Matthew Johnston, Ping Kang, Adam R Konopka, Noah Lepola, Carolyn J Presley, Marissa J Schafer, Joan Serrano, Benjamin D Singer, Min-Ae Song, Kristin I Stanford, Jackson Taylor, Wei Wei, Chung-Yang Yeh, Lei Zhang, Rozalyn M Anderson, Hua Bai, Paul D Robbins, Dudley W Lamming, Maria M Mihaylova, Mauricio Rojas, Ana L Mora
    • The Fourth Annual Symposium of the Midwest Aging Consortium
      Jinoh Kim, Rochelle Buffenstein, Anne M Bronikowski, Natalia-Del Pilar Vanegas, Lorena Rosas, Paula Agudelo-Garcia, Ana L Mora, Mauricio Rojas, Davis A Englund, Nathan K LeBrasseur, Allancer Nunes, Paul D Robbins, Marian L Kohut, Siddhant Kothadiya, Rizia Bardhan, Christina D Camell, Ines Sturmlechner, Jörg J Goronzy, Chung-Yang Yeh, Dudley W Lamming, Shijiao Huang, Scott F Leiser, Wilber Escorcia, Matthew S Gill, Jackson R Taylor, Stephen L Helfand, Sovannarith Korm, Kristin E Gribble, Mariana Pehar, Magdalena Blaszkiewicz, Kristy L Townsend, Eric R McGregor, Rozalyn M Anderson, Lukas Stilgenbauer, Marianna Sadagurski, Alicia Taylor, Elizabeth McNeill, Thomas Stoeger, Hua Bai
    • Depth-Dependent Contributions of Various Vascular Zones to Cerebral Autoregulation and Functional Hyperemia: An In-Silico Analysis
      Hadi Esfandi, Mahshad Javidan, Rozalyn M Anderson, Ramin Pashaie

    Dr. Anderson’s research focuses on understanding interconnections between nutrition, metabolism, health, and longevity. Reduced calorie intake without malnutrition, a strategy known as caloric restriction (CR), delays aging the onset of age-related disorders in many different species including yeast, worms, flies and mice. Dr. Anderson has shown that calorie restriction also has a beneficial effect in rhesus monkeys, improving survival and lowering the incidence of age-related diseases. The goal of the Anderson laboratory is to uncover the mechanisms behind CR; by identifying the key regulatory pathways recruited by CR, the team is focused on gleaning novel insights into disease etiology and what contributes to the increased risk for disease with age. These discoveries will enable new strategies to treat and prevent age-related diseases and conditions.