Nutrition and Metabolism PhD Program

    Nutrition researchers are a critical part of our society as they examine the complex interplay between nutrients, health, and disease, spanning from the individual to populations. With careers as faculty or independent scientists in academia, industry, and government, graduates of the Nutrition and Metabolism (N&M) PhD Program are at the forefront of research. They are making important contributions linking diet to the maintenance of health and impact on disease prevalence, and educating the public on the critical role of diet in the maintenance of optimal health throughout the life cycle.

    Research

    52 faculty trainers across 17 departments provide extensive interdisciplinary training opportunities in molecular, human and animal nutrition research.

    Program Requirements

    Our flexible curriculum provides core nutrition and metabolism coursework, with ample opportunities for elective coursework and minors.

    Student Life

    Gain a world-class education in a world-class city. Madison is a vibrant and inclusive community, and is consistently ranked as one of the best places to live in the U.S. for quality of life.

    News & Events

    • N&M trainer research featured in GROW magazine

      N&M faculty trainer Snehal Chaudhari reveals how gastrointestinal microbes influence disease, a critical step toward developing better therapies. Read the full interview here.

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    • 27th Annual Nutrition and Metabolism Poster Session

      The Department of Nutritional Sciences held its 27th Annual Nutrition and Metabolism Poster Session on March 7. The event format had many changes this year, including moving the event to Friday afternoon, changing up the venue, and opening to poster competition to anyone from Nutrition and Metabolism Graduate Program faculty trainer’s labs. The grand prize…

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    • Federico Rey and Maggie Alexander headline UW’s Crossroads of Ideas 2025 series

      N&M trainers Drs. Federico Rey and Maggie Alexander will be featured in the 2025 Crossroads of Ideas series, hosted by the Wisconsin Institute for Discovery. Rey’s talk focuses on “Alzheimer’s and the Gut-Brain Superhighway”, while Alexander’s talk is about “Microbes, Addiction, and Immunity”. You can find all video archives and learn more about Crossroads of…

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    • Register for the N&M Virtual Info Session

      Learn more about the Nutrition and Metabolism Graduate Program at a virtual informational session on November 18 at 5:00pm! We will discuss the curriculum, funding opportunities, application requirements, and student life! RSVP here for the link.

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    Recent Publications

    Hermanson JB, Tolba SA, Gazi MAChrisler EA, Kaur M, Sidebottom AM, Liu Y, Martinez-Boggio G, Lucas LN, Amador-Noguez D, Rey FE, Leone VAGut microbes mediate the synergistic effects of dietary cholesterol and saturated fat in driving fibrosing MASH. Gut Microbes. 2026 Dec 31;18(1):2668121.

    Wagner MR, Pintozzi NG, Schoff BM, Gold MI, Kasper RH, Steele NG, Blum B. Stromal and Neuronal Sources of Slit2/3 Ligands in the Adult Pancreas Exhibit Distinct Expression Patterns Independent of Robo2 Receptor Expression in the Islet. bioRxiv [Preprint]. 2026 May 18:2026.05.15.725534.

    Knopf BA, Grunow I, Anderson B, Rihawi T, Sonsalla MM, Calubag MF, Babygirija R, Liu Y, Xiao F, Yeh CY, Lamming DWFemale resistance to the metabolic benefits of protein restriction is reversed by ovariectomy in mice. bioRxiv [Preprint]. 2026 Apr 3:2026.03.31.715667.

    Williams J, Kim WS, Danner R, Cho J, Silva BF, Harris DA, Rey FE, Chaudhari SN. Atlas of one-carbon metabolism in conventional and germ-free mice reveals folate as a key determinant of biochemical pathways. Nat Metab. 2026 Apr;8(4):924-940.

    Cho J, Danner R, Kim WS, Williams J, Singh A, Han JA, Van Vranken JG, Walker AS, Rhoads T, Chaudhari SNMicrobial metabolism of methotrexate produces a STAT3 signaling molecule that alleviates gut inflammation. bioRxiv [Preprint]. 2026 Mar 12:2026.03.11.711168.

    McGregor ER, Osterbauer KJ, Gustafson GE, Clark JP, Rhoads TW, Anderson RMAdiponectin and aging: Mechanistic insights, clinical paradox, and therapeutic horizons. Ageing Res Rev. 2026 May;117:103059.

    Armstrong MT, Antunes KWillis NBMeyer MBPierre JF, Ozturk G. Whey Protein Phospholipid Concentrate and Its Fractions as a Diet Intervention Enhance Bone Health and Alter the Gut Microbiome in Weanling Mice. FASEB J. 2025 Dec 15;39(23):e71260. doi: 10.1096/fj.202502683R. PMID: 41363910; PMCID: PMC12687760.

    Trautman ME, Green CL, MacArthur MR, Chaiyakul K, Alam YH, Yeh CY, Babygirija R, James I, Gilpin M, Zelenovskiy E, Green M, Marshall RN, Raskin A, Sonsalla MM, Flores VSimcox JA, Ong IM, Malecki KC, Jang C, Lamming DW. Dietary isoleucine content modulates the metabolic and molecular response to a Western diet in mice. Mol Metab. 2025 Nov;101:102248.

    Hermanson JB, Tolba SA, Gazi MA, Chrisler EA, Kaur M, Sidebottom AM, Liu Y, Martinez-Boggio G, Lucas LNAmador-Noguez DRey FELeone VAGut microbes mediate the synergistic effects of dietary cholesterol and saturated fat in driving fibrosing MASH. bioRxiv [Preprint]. 2025 Jul 21:2025.07.16.665145.