Nathan Welham

Professor of Surgery

Protein metabolism; retinoids in epithelial biology; voice and swallow disorders

welham@surgery.wisc.edu

Wisconsin Institutes for Medical Research (WIMR) BLDG. 1485
1111 Highland Ave.
Madison, WI 53705-2275

Type: Faculty Trainer, MANTP Trainer

Department: Surgery

Education

BSLT (Hons I), University of Canterbury, Christchurch, New Zealand
MSLT (Dist), University of Canterbury, Christchurch, New Zealand
PhD, University of Wisconsin-Madison, Madison, WI

Rapid expansion of primary human vocal fold epithelial cells via targeted pathway inhibition and anchorage-independent sphere culture

Xudong Shi, Ryo Suzuki, Haiyan Lu, Hua Zhang, Lingjun Li, Nathan V Welham

Cell reports methods. 2026 March 7.
Agreement Between Hypernasality Ratings and Nasalance Scores in Spanish-English Bilingual Patients with Cleft Palate

Jacqueline Burpee, Evalise Dexter, John H Munday, Nathan V Welham

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association. 2025 December 26.
Synthesis of 13C2-Retinyl Acetate and Dose Preparation for Retinol Isotope Dilution Tests

Sherry A Tanumihardjo, Jesse Sheftel, Khushi Tanna, Molly Fjalstad, Nathan V Welham, Christopher R Davis, Bryan M Gannon

Journal of visualized experiments : JoVE. 2025 September 8.
Single-cell lipidomics enabled by dual-polarity ionization and ion mobility-mass spectrometry imaging

Hua Zhang, Yuan Liu, Lauren Fields, Xudong Shi, Penghsuan Huang, Haiyan Lu, Andrew J Schneider, Xindi Tang, Luigi Puglielli, Nathan V Welham, Lingjun Li

Nature communications. 2023 August 25.
On-tissue amidation of sialic acid with aniline for sensitive imaging of sialylated N-glycans from FFPE tissue sections via MALDI mass spectrometry

Hua Zhang, Xudong Shi, Yuan Liu, Bin Wang, Meng Xu, Nathan V Welham, Lingjun Li

Analytical and bioanalytical chemistry. 2022 January 24.
An atlas of protein turnover rates in mouse tissues

Zach Rolfs, Brian L Frey, Xudong Shi, Yoshitaka Kawai, Lloyd M Smith, Nathan V Welham

Nature communications. 2021 November 27.
Quantification and molecular imaging of fatty acid isomers from complex biological samples by mass spectrometry

Hua Zhang, Meng Xu, Xudong Shi, Yuan Liu, Zihui Li, Justin C Jagodinsky, Min Ma, Nathan V Welham, Zachary S Morris, Lingjun Li

Chemical science. 2021 July 1.
High-resolution magnetic resonance and mass spectrometry imaging of the human larynx

Ayami Ohno Kishimoto, Yo Kishimoto, Xudong Shi, Elizabeth B Hutchinson, Hua Zhang, Yatao Shi, Gisele Oliveira, Lingjun Li, Nathan V Welham, Ian J Rowland

Journal of anatomy. 2021 May 25.
On-Tissue Derivatization with Girard’s Reagent P Enhances N-Glycan Signals for Formalin-Fixed Paraffin-Embedded Tissue Sections in MALDI Mass Spectrometry Imaging

Hua Zhang, Xudong Shi, Nhu Q Vu, Gongyu Li, Zihui Li, Yatao Shi, Miyang Li, Bin Wang, Nathan V Welham, Manish S Patankar, Paul Weisman, Lingjun Li

Analytical chemistry. 2020 September 1.
Proteomic and Genomic Methylation Signatures of Idiopathic Subglottic Stenosis

Stephen S Schoeff, Xudong Shi, William G Young, Chad W Whited, Resha S Soni, Peng Liu, Irene M Ong, Seth H Dailey, Nathan V Welham

The Laryngoscope. 2020 July 4.

Dr. Welham’s research interests include vocal fold mucosal biology; extracellular matrix-focused proteomics; and vitamin A transport, storage and function.

Dr. Welham was awarded a five-year, $2.7 million research grant from the National Institute on Deafness and Other Communication Disorders. Read more here.

Certificates: American Speech Language Hearing Association Certificate of Clinical Competency
Licenses: Speech, Language Pathology