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Veterans Administration Hosp
2500 Overlook Ter GRECC D5214
Madison WI 53705-2254
Dr. Rozalyn Anderson is a faculty member of the Division of Geriatrics and Gerontology and the Division of Endocrinology, Diabetes and Metabolism in the Department of Medicine. She is affiliated with the Department of Nutritional Sciences and the Institute on Aging. She serves as Health Officer at the Geriatric Research Education and Clinical Center at the William S. Middleton Memorial Veterans Hospital. Her research focuses on the fundamental biology of aging and what creates the age-associated increase in vulnerability to a spectrum of diseases and disorders including cancer, diabetes, cardiovascular disease, and neurodegeneration.
- Systems biology analysis of vasodynamics in mouse cerebral arterioles during resting state and functional hyperemia
- Dietary restriction in aging and longevity
- Adiponectin and aging: Mechanistic insights, clinical paradox, and therapeutic horizons
- Acetyl-CoA availability regulates neuronal metabolism, growth, and synaptic activity
- How and why does aging occur? Updating evolutionary theory to meet a new era of data
- The Sixth Annual Symposium of the Midwest Aging Consortium
- Aging-linked systemic lipid signature is reprogrammed by caloric restriction in rhesus monkeys
- Caloric Restriction Reprograms Adipose Tissues in Rhesus Monkeys
- Author Correction: ImAge quantitates aging and rejuvenation
- Position paper: leveraging non-human primate (NHP) specificities to accelerate Parkinson's disease and ageing research
- Depth-dependent contributions of various vascular zones to cerebral autoregulation and functional hyperemia: An in-silico analysis
- The ongoing challenge of slowing ageing through drug discovery
- Caloric restriction reprograms adipose tissues in rhesus monkeys
- Neuron-specific isoform of PGC-1α regulates neuronal metabolism and brain aging
- Test of Rapamycin in Aging Dogs (TRIAD): study design and rationale for a prospective, parallel-group, double-masked, randomized, placebo-controlled, multicenter trial of rapamycin in healthy middle-aged dogs from the Dog Aging Project
Dr. Anderson’s research focuses on understanding interconnections between nutrition, metabolism, health, and longevity. Reduced calorie intake without malnutrition, a strategy known as caloric restriction (CR), delays aging the onset of age-related disorders in many different species including yeast, worms, flies and mice. Dr. Anderson has shown that calorie restriction also has a beneficial effect in rhesus monkeys, improving survival and lowering the incidence of age-related diseases. The goal of the Anderson laboratory is to uncover the mechanisms behind CR; by identifying the key regulatory pathways recruited by CR, the team is focused on gleaning novel insights into disease etiology and what contributes to the increased risk for disease with age. These discoveries will enable new strategies to treat and prevent age-related diseases and conditions.