Ines Sturmlechner, Sarah A Ashiqueali, Hélène Martini, Karla Valdivieso, Ana Catarina Franco, Prashanth Guthikonda, Andrew J Dosch, Luis I Prieto, Niels C Asmussen, Amanda S Latham, James T Redden, Ethan A Leitschuh, Douglas G Mashek, João F Passos, Jhonny Rodriguez-Lopez, T Blake Monroe, David A Bernlohr, Paul D Robbins, Bailey A Knopf, Dudley W Lamming, Matthew J Johnston, Holly M Brown-Borg, Spencer A Tye, Timothy W Rhoads, David M Gate, Bennett G Childs, Darren J Baker, Xinna Li, In Hwa Jang, Christina D Camell, Zachary Miller, Hemali Phatnani, Adam R Konopka, Andrew J Haak, Natalia Vanegas-Avendano, Ramya N Akula, Ajinkya R Limkar, William A Ricke, Scott F Leiser, Jacinta Correia, Hua Bai, Szczepan Olszewski, Kenneth L Seldeen, G R Scott Budinger, Luisa C Morales-Nebreda, Deborah R Winter, Shelly K Mccrady-Spitzer, Rozalyn M Anderson, Maria M Mihaylova, Mauricio Rojas, Ana L Mora, Nathan K Lebrasseur, Marissa J Schafer
Orion S Willoughby, Anna S Nichenko, Matthew H Brisendine, Niloufar Amiri, Shelby N Henry, Daniel S Braxton, John R Brown, Braeden J Kraft, Kalyn S Jenkins, Adele K Addington, Alexey V Zaitsev, Steven T Burrows, Ryan P McMillan, Haiyan Zhang, Spencer A Tye, Charles P Najt, Siobhan E Craige, Timothy W Rhoads, Junco S Warren, Joshua C Drake
Orion S Willoughby, Anna S Nichenko, Matthew H Brisendine, Niloufar Amiri, Shelby N Henry, Daniel S Braxton, John R Brown, Braeden J Kraft, Kalyn S Jenkins, Adele K Addington, Alexey V Zaitsev, Steven T Burrows, Ryan P McMillan, Haiyan Zhang, Spencer A Tye, Charles P Najt, Siobhan E Craige, Timothy W Rhoads, Junco S Warren, Joshua C Drake
Dylan C Souder, Eric R McGregor, Josef P Clark, Timothy W Rhoads, Tiaira J Porter, Kevin W Eliceiri, Darcie L Moore, Luigi Puglielli, Rozalyn M Anderson
Andrea Keller, Hua Bai, Scott Budinger, Susan Eliazer, Malene Hansen, Adam R Konopka, Luisa Morales-Nebreda, Charles P Najt, Veena Prahlad, Stella Victorelli, Colby J Vorland, Rong Yuan, Timothy W Rhoads, Maria M Mihaylova
Alex B Smith, Jonah P Schill, Ruth Gordillo, Grace E Gustafson, Timothy W Rhoads, Maggie S Burhans, Aimee T Broman, Ricki J Colman, Philipp E Scherer, Rozalyn M Anderson
Michaela E Murphy, Akilavalli Narasimhan, Alexis Adrian, Ankur Kumar, Cara L Green, Carolina Soto-Palma, Chathurika Henpita, Christina Camell, Christopher S Morrow, Chung-Yang Yeh, Claire E Richardson, Cristal M Hill, Darcie L Moore, Dudley W Lamming, Eric R McGregor, Heather A Simmons, Heidi H Pak, Hua Bai, John M Denu, Josef Clark, Judith Simcox, Kishore Chittimalli, Korbyn Dahlquist, Kyoo-A Lee, Mariah Calubag, Mark Bouska, Matthew J Yousefzadeh, Michelle Sonsalla, Reji Babygirija, Rong Yuan, Tadataka Tsuji, Timothy Rhoads, Vinal Menon, Yagna Pr Jarajapu, Yun Zhu
Katherine A Overmyer, Timothy W Rhoads, Anna E Merrill, Zhan Ye, Michael S Westphall, Amit Acharya, Sanjay K Shukla, Joshua J Coon
Work in the GERAM (Gene Expression Regulation of Aging and Metabolism) lab, directed by Dr. Rhoads, focuses on understanding the molecular regulation of aging and metabolism through the use of caloric restriction (CR). CR is a dietary intervention and model of delayed aging; CR results in extended lifespan in numerous model organisms. This is of direct relevance for human health, as advanced age is the largest risk factor for numerous chronic diseases – cancer, diabetes, cardiovascular disease, and neurodegeneration, to name a few. However, the molecular mechanisms connecting reduced caloric intake with enhanced longevity and reduced chronic disease vulnerability remain poorly understood. The GERAM lab focuses on mechanisms of gene expression regulation, including protein post-translational modification, mRNA processing, and expression regulation via endogenous small RNA. Tools used include both wet lab and dry lab analytical methods, with a substantial interest in integrative models that produce systems-level insights.
